A Study on the Antioxidant Activity and Tissues Selective Inhibition of Lipid Peroxidation by Saponins from the Roots of Platycodon grandiflorum

American journal of chinese medicine 2009

Platycodi Radix is the root of Platycodon grandiflorum (Jacq.) A. DC and has been used its a traditional medicine in China. According ...

Induction of apoptosis in HT-29 colon cancer cells by crude saponin from Platycodi Radix

Food and chemical toxicology 2009

This study examined the apoptotic effects of crude saponins acquired from the roots of Platycodon grandiflorum (SPR) in HT-29 human co...

Protective effect of saponins derived from the roots of Platycodon grandiflorum against carbon tetrachloride induced hepatotoxicity in mice

Food and chemical toxicology 2008

The purpose of this study was to investigate the protective effects of the saponins isolated from the root of Platycodi Radix (Changki...

Protective effects of Platycodi radix on alcohol-induced fatty liver

Bioscience biotechnology and biochemistry 2007

The protective effects of Platycodi radix (PR), the root of Platycodon grandiflorum A. DC, on alcohol-induced fatty liver and possible...

Antihyperglycemic effects of Platycodon grandiflorum (Jacq.) a. DC. extract on streptozotocin-induced diabetic mice

Plant foods for human nutrition 2007

The root of Platycodon grandiflorum (Jacq.) A. DC has been reported to have a wide range of health benefits in oriental food. This stu...

Chemopreventive effect of saponins derived from roots of Platycodon grandiflorum on 4-(methyinitrosamino)-1-(3-pyridyl)-1-butanone-induced lung turnorigenesis in A/J mice

Archives of pharmacal research 2006

This study examined the chemopreventive effect of saponins that were isolated from the roots of Platycodon grandiflorum A. DC (Campanu...

In vitro inhibitory effect of triterpenoidal saponins from Platycodi Radix on pancreatic lipase

Archives of pharmacal research 2005

In the process of investigating anti-obesity effect of Platycodi Radix, we found that aqueous extract of Platycodi Radix might inhibit...

Suppressive effects of Platycodon grandiflorum on the progress of carbon tetrachloride-induced hepatic fibrosis

Archives of pharmacal research 2004

The suppressive effects of Platycodi Radix (Changkil: CK), the root of Platycodon grandiflorum A. DC (Campanulaceae), on the progress ...

An aqueous extract of Platycodi radix inhibits LPS-induced NF-kappa B nuclear translocation in human cultured airway epithelial cells

International journal of molecular medicine 2004

We investigated the effects of aqueous extract from Platycodi radix (AEPR), a traditional drug used to treat acute lung inflammatory d...

Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice

Journal of nutrition 2002

We examined the effects of crude saponins isolated from Platycodi radix on the degree on fat storage induced in mice by feeding a high...