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Hepato-protective effects of loganin, iridoid glycoside from Corni Fructus, against hyperglycemia-activated signaling pathway in liver of type 2 diabetic db/db mice
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Toxicology 2011
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Accumulating evidence indicates that uncontrolled diabetes leads to the progression of diabetic complications such as liver disorder. ...
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Evaluation of Morroniside, Iridoid Glycoside from Corni Fructus, on Diabetes-Induced Alterations such as Oxidative Stress, Inflammation, and Apoptosis in the Liver of Type 2 Diabetic db/db Mice
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Biological & pharmaceutical bulletin 2011
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The present study was conducted to examine whether morroniside has an ameliorative effect on diabetes-induced alterations such as oxid...
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Oleanolic Acid and Ursolic Acid Derived from Cornus officinalis Sieb. et Zucc. Suppress Epidermal Growth Factor- and Phorbol Ester-induced MUC5AC Mucin Production and Gene Expression from Human Airway Epithelial Cells
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Phytotherapy research 2011
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In this study, the effects of oleanolic acid and ursolic acid on MUC5AC mucin production and gene expression induced by epidermal grow...
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Anti-oxidative effects of flavonoids enriched Corni fructus extract and the mechanism
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African journal of pharmacy and pharmacology 2011
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We tested to determine if Corni fructus extract has antioxidant activities and explored its potential mechanism in terms of iNOS and C...
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Inhibitory Effects of Corni Fructus Extract on Angiogenesis and Adipogenesis
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Korean journal of physiology & pharmacology 2011
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Natural products in Chonnam, Korea were screened via anti-angiogenesis experiments, and 1 candidate product was identified, Corni fruc...
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The Effects of Corni Fructus Extract and Its Fractions Against alpha-Glucosidase Inhibitory Activities in Vitro and Sucrose Tolerance in Normal Rats
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American journal of chinese medicine 2011
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Corni Fructus (Cornus officinalis Sieb. et Zucc.) is a traditional medicine exerting multifaceted protective effects against diabetes ...
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Effects of Fraction Obtained From Korean Corni Fructus Extracts Causing Anti-Proliferation and p53-Dependent Apoptosis in A549 Lung Cancer Cells
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Nutrition and cancer-an international journal 2011
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Corni Fructus has traditionally been used as herbal medicine for the treatment of tuberculosis, asthma, hepatitis, and chronic nephrit...
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Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice
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European journal of pharmacology 2010
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Previously, we have reported that Corni Fructus possessed hypoglycemic and hypocholesterolemic effects in streptozotocin-induced type ...
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Antidiabetic and renoprotective effects of Corni Fructus extract in db/db mice
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Molecular & cellular toxicology 2010
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This study investigated the effect of Corni Fructus (Cornus officinalis Sieb. et Zucc.) extract on hyperglycemia, renal dysfunction an...
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Protective effect of 5-hydroxymethylfurfural derived from processed Fructus Corni on human hepatocyte LO2 injured by hydrogen peroxide and its mechanism
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Journal of ethnopharmacology 2010
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Aim of the study The aim of the present study was to evaluate the putative protective effect of 5-hydroxymethylfurfural (5-HMF) derive...
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