Determination of 5-hydroxymethyl-2-furaldehyde of crude and processed Fructus Corni in freely moving rats using in vivo microdialysis sampling and liquid chromatography

Pharmacognosy magazine 2011

"Background: Fructus Corni is derived from the dry ripe sarcocarp of Cornus officinalis Sieb. et Zucc. 5-hydroxymethyl-2-furaldehyde (...

Identification of metabolites of crude and processed Fructus Corni in rats by microdialysis sampling coupled with electrospray ionization linear quadrupole ion trap mass spectrometry

Journal of pharmaceutical and biomedical analysis 2011

A microdialysis (MD) sampling coupled with electrospray ionization linear quadrupole ion trap mass spectrometry (LTQ-MS(n)) method has...

Evaluation of the Potential Hypoglycemic and Beta-Cell Protective Constituents Isolated from Corni Fructus To Tackle Insulin-Dependent Diabetes Mellitus

Journal of agricultural and food chemistry 2011

"Corni fructus is the fruit of Cornus officinalis Sieb. et Zucc. and has attracted much interest due to its traditional applications a...

Qualitative and quantitative analysis of Fructus Corni using ultrasound assisted microwave extraction and high performance liquid chromatography coupled with diode array UV detection and time-of-flight mass spectrometry

Journal of pharmaceutical and biomedical analysis 2011

The first successful combination of ultrasound assisted microwave extraction (UAME) with liquid chromatography analysis is described f...

Analysis of the interactions of multicomponents in Cornus officinalis Sieb. et Zucc. with human serum albumin using on-line dialysis coupled with HPLC

Journal of chromatography b-analytical technologies in the biomedical and life sciences 2011

Interactions of three iridoid glycosides extracted from Cornus officinalis Sieb. et Zucc. (CIG) with protein were simultaneously explo...

Galloyl Glucoses from the Seeds of Cornus officinalis with Inhibitory Activity against Protein Glycation, Aldose Reductase, and Cataractogenesis ex Vivo

Biological & pharmaceutical bulletin 2011

"In an ongoing project directed toward the discovery of novel treatments for diabetic complications from traditional herbal medicines,...

A Rapid and Sensitive Assay for Determining the Main Components in Processed Fructus Corni by UPLC-Q-TOF-MS

Chromatographia 2011

"Fructus Corni is the dried sarcocarp of Cornus officinalis Sieb. et Zucc., and has been widely used as an important traditional Chine...

Apoptotic action of ursolic acid isolated from Corni fructus in RC-58T/h/SA#4 primary human prostate cancer cells

Bioorganic & medicinal chemistry letters 2010

Ursolic acid (3 beta-hydroxy-urs-12-en-28-oic acid) is a major biological active component of Corni fructus that is known to induce ap...

Isolation and structural characterization of a polysaccharide FCAP1 from the fruit of Cornus officinalis

Carbohydrate research 2010

A water-soluble polysaccharide, FCAP1, was isolated from an alkaline extract from the fruits of Cornus officinalis. Its molecular weig...

Investigation on the morphological protective effect of 5-hydroxymethylfurfural extracted from wine-processed Fructus corni on human L02 hepatocytes

Journal of ethnopharmacology 2010

Aim: To determine the mode of action of 5-hydroxymethylfurfural (5-HMF) extracted from wine-processed Fructus corni on hepatoprotectiv...